Amino Acids

Amino acids are chemical molecules with amino and carboxylate functional groups as well as a side chain that is unique to each amino acid. Amino Acids are chemical substances that combine to produce proteins, which is why they are known as the building blocks of proteins. These biomolecules have a role in a variety of biological and chemical functions in the human body and are essential for human growth and development. There are around 300 amino acids found in nature. Amino acids' general features include:

1. A high melting and boiling point.

2. Amino acids are crystalline solids that are white in color.

3. Few amino acids have a pleasant, tasteless, or bitter flavour.

4. The majority of amino acids are water-soluble and insoluble in organic solvents.

There are 20 amino acids found in nature, all of which have the same structural features: an amino group (-NH3+), a carboxylate group (-COO-), and a hydrogen-bonded to the same carbon atom. Their side-chain, known as the R group, distinguishes them from one another. The - carbon of each amino acid is connected to four distinct groups namely: Amino group, COOH, Hydrogen atom, and Sidechain.

Amino acids have a general structure which can be represented as:

 

Figure 3: Structure of Amino Acid

Our bodies can easily produce a few non-essential amino acids out of a total of 20 amino acids. Alanine, asparagine, arginine, aspartic acid, glutamic acid, cysteine, glutamine, proline, glycine, serine, and tyrosine are examples of these amino acids.

Besides these, there are nine other amino acids that are extremely important because our bodies cannot make them. Isoleucine, histidine, lysine, leucine, phenylalanine, tryptophan, methionine, threonine, and valine are examples of important amino acids.

Amino acids are essential for a variety of biological and chemical tasks in our bodies, including tissue construction and repair, enzyme production and activity, food digestion, molecule transportation, and so on. Only a few amino acids can be synthesized by our bodies, thus the rest, known as essential amino acids, must be obtained from protein-rich foods in our daily diet. Plant-based foods with high levels of amino acids include broccoli, beans, beets, pumpkin, cabbage, almonds, dry fruits, chia seeds, oats, peas, carrots, cucumber, green leafy vegetables, onions, soybeans, whole grain, peanuts, legumes, lentils, and so on. Apples, bananas, berries, figs, grapes, melons, oranges, papaya, pineapple, and pomegranates are high in amino acids.Dairy products, eggs, seafood, poultry, beef, pork, and other animal products are examples of other animal goods.

Functions of Essential Amino acids

1. Phenylalanine helps in maintaining a healthy nervous system and in boosting memory power.

2. Valine acts as an important component in promoting muscle growth.

3. Threonine helps in promoting the functions of the immune system.

4. Tryptophan is involved in the production of vitamin B3 and serotonin hormones. This serotonin hormone plays a vital role in maintaining our appetite, regulating sleep and boosting our moods.

5. Isoleucine plays a vital role in the formation of hemoglobin, stimulating the pancreas to synthesize insulin, and transporting oxygen from the lungs to the various parts.

6. Methionine is used in the treatment of kidney stones, maintaining healthy skin and also used in controlling invade of pathogenic bacteria.

7. Leucine is involved in promoting protein synthesis and growth hormones.

8. Lysine is necessary for promoting the formation of antibodies, hormones, and enzymes and in the development and fixation of calcium in bones.

9. Histidine is involved in many enzymatic processes and in the synthesizing of both red blood cells (erythrocytes) and white blood cells (leukocytes).

Functions of Non-Essential Amino acids

1. Alanine functions by removing toxins from our body and in the production of glucose and other amino acids.

2. Cysteine acts as an antioxidant and provides resistance to our body; it is important for making collagen. It affects the texture and elasticity of the skin

3. Glutamine promotes a healthy brain function and is necessary for the synthesis of nucleic acids – DNA and RNA.

4. Glycine is helpful in maintaining the proper cell growth, and its function, and it also plays a vital role in healing wounds. It acts as a neurotransmitter.

5. Glutamic acid acts as a neurotransmitter and is mainly involved in the development and functioning of the human brain.

6. Arginine helps in promoting the synthesis of proteins and hormones, detoxification in the kidneys, healing wounds, and maintaining a healthy immune system.

7. Tyrosine plays a vital role in the production of the thyroid hormones -T3 and T4, in synthesizing a class of neurotransmitters and melanin, which are natural pigments found in our eyes, hair, and skin.

8. Serine helps in promoting muscle growth and in the synthesis of immune system proteins.

9. Asparagine is mainly involved in the transportation of nitrogen into our body cells, formations of purines and pyrimidine for the synthesis of DNA, the development of the nervous system and improving our body stamina.

10. Aspartic acid plays a major role in metabolism and in promoting the synthesis of other amino acids.

11. Proline is mainly involved in the repairing of the tissues and the formation of collagen, preventing the thickening and hardening of the walls of the arteries (arteriosclerosis) and in the regeneration of new skin.